| Host: | Mouse |
| Applications: | FIA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-HE4 for use in FIA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 4505 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | 50 mM citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Concentration: | 5.0 mg/ml (+/-10 %) |
| Storage Instruction: | Store at 2–8 °C, and do not freeze. |
| Specificity: | Antibody recognizes human epididymis protein 4 (HE4). Does not recognize cancer antigens CA125 or CA19-9 |
| Immunogen: | Not determined |
| Tissue Specificity | Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. |
| Function | Broad range protease inhibitor. |
| Protein Name | Wap Four-Disulfide Core Domain Protein 2Epididymal Secretory Protein E4Major Epididymis-Specific Protein E4Putative Protease Inhibitor Wap5 |
| Database Links | Reactome: R-HSA-9830364 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Wap Four-Disulfide Core Domain Protein 2 antibodyAnti-Epididymal Secretory Protein E4 antibodyAnti-Major Epididymis-Specific Protein E4 antibodyAnti-Putative Protease Inhibitor Wap5 antibodyAnti-WFDC2 antibodyAnti-HE4 antibodyAnti-WAP5 antibody |
Information sourced from Uniprot.org