| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HCRTR1 |
| Gene ID: | 3061 |
| Uniprot ID: | OX1R_HUMAN |
| Immunogen Region: | 150-250 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human HCRTR1 (NP_001516.2). |
| Immunogen Sequence: | HPLLFKSTARRARGSILGIW AVSLAIMVPQAAVMECSSVL PELANRTRLFSVCDERWADD LYPKIYHSCFFIVTYLAPLG LMAMAYFQIFRKLWGRQIPG T |
| Function | Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding. |
| Protein Name | Orexin/Hypocretin Receptor Type 1Hypocretin Receptor Type 1Orexin Receptor Type 1Ox-1-ROx1-ROx1r |
| Database Links | Reactome: R-HSA-389397Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Orexin/Hypocretin Receptor Type 1 antibodyAnti-Hypocretin Receptor Type 1 antibodyAnti-Orexin Receptor Type 1 antibodyAnti-Ox-1-R antibodyAnti-Ox1-R antibodyAnti-Ox1r antibodyAnti-HCRTR1 antibody |
Information sourced from Uniprot.org