| Host: | Mouse |
| Applications: | CLIA/FIA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-hCG beta for use in CLIA and FIA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 5012 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Concentration: | 5.0 mg/ml (+/-10 %) |
| Storage Instruction: | Store at 2–8 °C, and do not freeze. |
| Specificity: | Antibody recognizes human chorionic gonadotropin free beta subunit. Does not recognize intact hCG, hCGa, LH, FSH, or TSH |
| Immunogen: | Beta-7 as described in Berger et al. (2013). The antibody recognizes free hCGß subunit. |
| Background | Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced in pregnancy by the developing embryo soon after conception and later by the syncytiotrophoblast (part of the placenta). Its role is to prevent the disintegration of the corpus luteum of the ovary and thereby maintain progesterone production that is critical for a pregnancy in humans. Early pregnancy testing, in general, is based on the detection of hCG. hCG is produced also by some tumors, but it is not known whether this production is a contributing cause or an effect of tumorigenesis. |
Information sourced from Uniprot.org

