![Anti-hCG-beta antibody [5H4-E2] (STJ16100284)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149002/302092/STJ16100284_1__22437.1646940351.jpg?c=1 "Anti-hCG-beta antibody [5H4-E2] (STJ16100284)")
![Anti-hCG-beta antibody [5H4-E2] (STJ16100284)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149002/302092/STJ16100284_1__22437.1646940351.jpg?c=1 "Anti-hCG-beta antibody [5H4-E2] (STJ16100284)")
| Short Description : | Mouse monoclonal anti-hCG-beta for use in IHC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 5H4-E2 |
| Isotype: | IgG1k |
| Conjugation: | Unconjugated |
| Concentration: | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Purification: | Affinity purified from tissue culture. |
| Dilution Range: | Immunohistology (1-2 µg/ml for 30 min at RT; staining of formalin-fixed tissues requires no pre-treatment). |
| Formulation: | PBS with 0.02% Sodium Azide. |
| Storage Instruction: | Store for up to 1 year at 2-8°C upon receipt. |
| Immunogen: | A BALB/c mouse was hCG beta, conjugated to various carrier proteins. Fusion partner: SP-2/0-Ag14. |
| Background | 5H4-E2 reacts with hCG beta chain, which is specific for hCG. The alpha chain is identical among hCG, TSH, FSH and LH. While hCG is secreted in large quantities by normal trophoblasts, it is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. Besides trophoblastic tumors e.g. choriocarcinoma, large cell carcinoma, adenocarcinoma and squamous cell carcinoma of the lung are also positive in 90%, 60% and 20% of cases respectively. In hCG producing tumors, including also certain testicular and embryonic carcinomas, the beta chain is produced in higher quantities than the alpha or dimeric chains. hCG expression by non-trophoblastic tumors may indicate aggressive behavior. |
Information sourced from Uniprot.org
![Anti-hCG beta antibody [SM5035] (STJA0005035)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/180095/403364/STJA0005035_1__88917.1738950430.png?c=1 "Anti-hCG beta antibody [SM5035] (STJA0005035)")
