Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse/Rat/Monkey |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-HMG box-containing protein 1 (431-480 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:10000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | HBP1 |
Gene ID: | 26959 |
Uniprot ID: | HBP1_HUMAN |
Immunogen Region: | 431-480 aa |
Specificity: | HBP1 Polyclonal Antibody detects endogenous levels of HBP1 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human HBP1 at the amino acid range 431-480 |
Function | Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. |
Protein Name | Hmg Box-Containing Protein 1 Hmg Box Transcription Factor 1 High Mobility Group Box Transcription Factor 1 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Hmg Box-Containing Protein 1 antibody Anti-Hmg Box Transcription Factor 1 antibody Anti-High Mobility Group Box Transcription Factor 1 antibody Anti-HBP1 antibody |
Information sourced from Uniprot.org