| Host: | Mouse |
| Applications: | IHC-p |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-HBcAg for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | IHC205 |
| Conjugation: | Unconjugated |
| Formulation: | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Instruction: | Store at 2-8°C for up to 1 year. Do not freeze. |
| Specificity: | Tested and validated on liver infected with hepatitis b virus tissue. |
| Background | The hepatitis B core antigen (HBcAg) is an important target for antiviral response in chronic hepatitis B (CHB) patients. The studies have shown that HbcAg expressed in different subcellular location based on IHC staining patterns including cytoplasmic expression, nuclear expression, cytoplasmic and nuclear-mixed expression or negative expression. The different distributions in the hepatocyte nucleus and cytoplasm of CHB indicate the level of viral replication and histological activity. |
Information sourced from Uniprot.org