Anti-HAS1 antibody (80-390) (STJ112482)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HAS1 (80-390) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HAS1 |
| Gene ID | 3036 |
| Uniprot ID | HYAS1_HUMAN |
| Immunogen Region | 80-390 |
| Immunogen Sequence | RVAAAARGPLDAATARSVAL TISAYQEDPAYLRQCLASAR ALLYPRARLRVLMVVDGNRA EDLYMVDMFREVFADEDPAT YVWDGNYHQPWEPAAAGAVG AGAYREVEAEDPGRLAVEAL VRTRRCVCVAQRWGGKREVM YTAFKALGDSVDYVQVCDSD TRLDPMALLELVRVLDEDPR VGAVGGDVRILNPLDSWVSF LSSLRYWVAFNVERACQSYF HCVSCISGPLGLYRNNLLQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 80-390 of human HAS1 (NP_001514.2). |
Additional Info
| Tissue Specificity | Widely expressed. Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine. |
| Function | Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate. |
| Protein Name | Hyaluronan Synthase 1Hyaluronate Synthase 1Hyaluronic Acid Synthase 1Ha Synthase 1Huhas1 |
| Database Links | Reactome: R-HSA-2142850 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Hyaluronan Synthase 1 antibodyAnti-Hyaluronate Synthase 1 antibodyAnti-Hyaluronic Acid Synthase 1 antibodyAnti-Ha Synthase 1 antibodyAnti-Huhas1 antibodyAnti-HAS1 antibodyAnti-HAS antibody |
Information sourced from Uniprot.org