| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HAPLN1 |
| Gene ID: | 1404 |
| Uniprot ID: | HPLN1_HUMAN |
| Immunogen Region: | 165-354 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 165-354 of human HAPLN1 (NP_001875.1). |
| Immunogen Sequence: | PRLGRYNLNFHEAQQACLDQ DAVIASFDQLYDAWRGGLDW CNAGWLSDGSVQYPITKPRE PCGGQNTVPGVRNYGFWDKD KSRYDVFCFTSNFNGRFYYL IHPTKLTYDEAVQACLNDGA QIAKVGQIFAAWKILGYDRC DAGWLADGSVRYPISRPRRR CSPTEAAVRFVGFPDKKHKL YGVYCFRAYN |
| Tissue Specificity | Widely expressed. Weakly expressed in the brain. |
| Function | Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix. |
| Protein Name | Hyaluronan And Proteoglycan Link Protein 1Cartilage-Linking Protein 1Cartilage-Link ProteinProteoglycan Link Protein |
| Database Links | Reactome: R-HSA-3000178 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Hyaluronan And Proteoglycan Link Protein 1 antibodyAnti-Cartilage-Linking Protein 1 antibodyAnti-Cartilage-Link Protein antibodyAnti-Proteoglycan Link Protein antibodyAnti-HAPLN1 antibodyAnti-CRTL1 antibody |
Information sourced from Uniprot.org