Anti-H2BC3 antibody [Mix] (STJ97064)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenSynthetic Peptide of Histone H2B
STJ97064
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General Information

Short DescriptionMouse monoclonal anti-Histone H2B type 1-B for use in WB and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IF
HostMouse
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDMix
IsotypeIgG1
ConjugationUnconjugated
PurificationThe antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution RangeWB 1:1000-3000
IF 1:200
FormulationLiquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolH2BC3
Gene ID3018
Uniprot IDH2B1B_HUMAN
ImmunogenSynthetic Peptide of Histone H2B
SpecificityThe antibody detects endogenous Histone H2B protein.

Additional Info

Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Protein Name Histone H2b Type 1-B
H2b-Clustered Histone 3
Histone H2b.1
Histone H2b.f
H2b/F
Database Links Reactome: R-HSA-110328
Reactome: R-HSA-110329
Reactome: R-HSA-110330
Reactome: R-HSA-110331
Reactome: R-HSA-1221632
Reactome: R-HSA-171306
Reactome: R-HSA-1912408
Reactome: R-HSA-201722
Reactome: R-HSA-212300
Reactome: R-HSA-2299718
Reactome: R-HSA-2559580
Reactome: R-HSA-2559582
Reactome: R-HSA-2559586
Reactome: R-HSA-3214815
Reactome: R-HSA-3214847
Reactome: R-HSA-427359
Reactome: R-HSA-427389
Reactome: R-HSA-427413
Reactome: R-HSA-5250924
Reactome: R-HSA-5334118
Reactome: R-HSA-5578749
Reactome: R-HSA-5617472
Reactome: R-HSA-5625886
Reactome: R-HSA-5689880
Reactome: R-HSA-5693565
Reactome: R-HSA-5693571
Reactome: R-HSA-5693607
Reactome: R-HSA-606279
Reactome: R-HSA-68616
Reactome: R-HSA-69473
Reactome: R-HSA-73728
Reactome: R-HSA-73772
Reactome: R-HSA-8866654
Reactome: R-HSA-8936459
Reactome: R-HSA-8939236
Reactome: R-HSA-9018519
Reactome: R-HSA-912446
Reactome: R-HSA-9609690
Reactome: R-HSA-9610379
Reactome: R-HSA-9616222
Reactome: R-HSA-9670095
Reactome: R-HSA-9710421
Reactome: R-HSA-977225
Reactome: R-HSA-9821002
Reactome: R-HSA-9821993
Reactome: R-HSA-9841922
Reactome: R-HSA-9843940
Reactome: R-HSA-9843970
Reactome: R-HSA-9845323
Cellular Localisation Nucleus
Chromosome
Alternative Antibody Names Anti-Histone H2b Type 1-B antibody
Anti-H2b-Clustered Histone 3 antibody
Anti-Histone H2b.1 antibody
Anti-Histone H2b.f antibody
Anti-H2b/F antibody
Anti-H2BC3 antibody
Anti-H2BFF antibody
Anti-HIST1H2BB antibody

Information sourced from Uniprot.org

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