Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-H2BC21 antibody (18-68 aa) (STJ194032)

Name: Anti-H2BC21 antibody (18-68 aa) (STJ194032)
SKU: STJ194032
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenSynthesized peptide derived from the human H2B2E at the amino acid range 18-68

STJ194032

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General Information

Short Description	Rabbit polyclonal anti-Histone H2B type 2-E (18-68 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	1 mg/mL
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range	WB 1:500-2000
Formulation	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene Symbol	H2BC21
Gene ID	8349
Uniprot ID	H2B2E_HUMAN
Immunogen	Synthesized peptide derived from the human H2B2E at the amino acid range 18-68
Immunogen Region	18-68 aa
Specificity	This antibody detects endogenous levels of H2B2E at Human/Mouse

Additional Info

Function	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
Protein Name	Histone H2b Type 2-E H2b-Clustered Histone 21 Histone H2b-Gl105 Histone H2b.q H2b/Q
Database Links	Reactome: R-HSA-110328 Reactome: R-HSA-110329 Reactome: R-HSA-110330 Reactome: R-HSA-110331 Reactome: R-HSA-1221632 Reactome: R-HSA-171306 Reactome: R-HSA-1912408 Reactome: R-HSA-201722 Reactome: R-HSA-212300 Reactome: R-HSA-2299718 Reactome: R-HSA-2559580 Reactome: R-HSA-2559582 Reactome: R-HSA-2559586 Reactome: R-HSA-3214815 Reactome: R-HSA-3214847 Reactome: R-HSA-427359 Reactome: R-HSA-427389 Reactome: R-HSA-427413 Reactome: R-HSA-5250924 Reactome: R-HSA-5334118 Reactome: R-HSA-5578749 Reactome: R-HSA-5617472 Reactome: R-HSA-5625886 Reactome: R-HSA-5689880 Reactome: R-HSA-5693565 Reactome: R-HSA-5693571 Reactome: R-HSA-5693607 Reactome: R-HSA-606279 Reactome: R-HSA-68616 Reactome: R-HSA-69473 Reactome: R-HSA-73728 Reactome: R-HSA-73772 Reactome: R-HSA-8936459 Reactome: R-HSA-8939236 Reactome: R-HSA-9018519 Reactome: R-HSA-912446 Reactome: R-HSA-9609690 Reactome: R-HSA-9610379 Reactome: R-HSA-9616222 Reactome: R-HSA-9670095 Reactome: R-HSA-9710421 Reactome: R-HSA-977225 Reactome: R-HSA-9821002 Reactome: R-HSA-9821993 Reactome: R-HSA-9841922 Reactome: R-HSA-9843940 Reactome: R-HSA-9843970 Reactome: R-HSA-9845323
Cellular Localisation	Nucleus Chromosome
Alternative Antibody Names	Anti-Histone H2b Type 2-E antibody Anti-H2b-Clustered Histone 21 antibody Anti-Histone H2b-Gl105 antibody Anti-Histone H2b.q antibody Anti-H2b/Q antibody Anti-H2BC21 antibody Anti-H2BFQ antibody Anti-HIST2H2BE antibody

Information sourced from Uniprot.org

Citations

View product citations for antibody STJ194032 on CiteAb