Anti-H2AC21 antibody (15-65 aa) (STJ195952)

SKU:
STJ195952
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Histone H2A type 2-B (15-65 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:H2AC21
Gene ID:317772
Uniprot ID:H2A2B_HUMAN
Immunogen:Synthesized peptide derived from the human H2A2B at the amino acid range 15-65
Immunogen Region:15-65 aa
Specificity:This antibody detects endogenous levels of H2A2B at Human/Mouse
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Protein Name Histone H2a Type 2-B
H2a-Clustered Histone 21
Database Links Reactome: R-HSA-3214815
Reactome: R-HSA-3214847
Reactome: R-HSA-3214858
Reactome: R-HSA-5689603
Reactome: R-HSA-5689880
Reactome: R-HSA-5689901
Reactome: R-HSA-9609690
Reactome: R-HSA-9610379
Cellular Localisation Nucleus
Chromosome
Alternative Antibody Names Anti-Histone H2a Type 2-B antibody
Anti-H2a-Clustered Histone 21 antibody
Anti-H2AC21 antibody
Anti-HIST2H2AB antibody

Information sourced from Uniprot.org