| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Histone H1.10 (100-180 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | H1-10 |
| Gene ID: | 8971 |
| Uniprot ID: | H1X_HUMAN |
| Immunogen Region: | 100-180 aa |
| Specificity: | H1X Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 100-180 |
| Post Translational Modifications | Citrullination at Arg-62 (H1R54ci) by PADI4 takes place within the DNA-binding site of H1 and results in its displacement from chromatin and global chromatin decondensation, thereby promoting pluripotency and stem cell maintenance. |
| Function | Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. |
| Protein Name | Histone H1.10Histone H1x |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone H1.10 antibodyAnti-Histone H1x antibodyAnti-H1-10 antibodyAnti-H1FX antibody |
Information sourced from Uniprot.org