| Host: |
Rabbit |
| Applications: |
IHC/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Granzyme M (207-256 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC-P 1:50-200ELISA 1:10000-20000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GZMM |
| Gene ID: |
3004 |
| Uniprot ID: |
GRAM_HUMAN |
| Immunogen Region: |
207-256 aa |
| Specificity: |
The antibody detects endogenous Granzyme M |
| Immunogen: |
Synthetic peptide from the human protein at the amino acid range 207-256 |
| Function | Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells. |
| Protein Name | Granzyme MMet-1 Serine ProteaseHu-Met-1Met-AseNatural Killer Cell Granular Protease |
| Database Links | Reactome: R-HSA-173736 |
| Cellular Localisation | SecretedCytoplasmic GranuleGranules Of Large Granular Lymphocytes |
| Alternative Antibody Names | Anti-Granzyme M antibodyAnti-Met-1 Serine Protease antibodyAnti-Hu-Met-1 antibodyAnti-Met-Ase antibodyAnti-Natural Killer Cell Granular Protease antibodyAnti-GZMM antibodyAnti-MET1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
