Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-GULP1 (1-130) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GULP1 |
Gene ID: |
51454 |
Uniprot ID: |
GULP1_HUMAN |
Immunogen Region: |
1-130 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human GULP1 (NP_057399.1). |
Immunogen Sequence: |
MNRAFSRKKDKTWMHTPEAL SKHFIPYNAKFLGSTEVEQP KGTEVVRDAVRKLKFARHIK KSEGQKIPKVELQISIYGVK ILEPKTKEVQHNCQLHRISF CADDKTDKRIFTFICKDSES NKHLCYVFDS |
Tissue Specificity | Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary. |
Function | May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6. |
Protein Name | Ptb Domain-Containing Engulfment Adapter Protein 1Cell Death Protein 6 HomologPtb Domain Adapter Protein Ced-6Protein Gulp |
Cellular Localisation | CytoplasmMay Associate With The Cytoplasmic Side Of The Plasma Membrane And Early Endosomes |
Alternative Antibody Names | Anti-Ptb Domain-Containing Engulfment Adapter Protein 1 antibodyAnti-Cell Death Protein 6 Homolog antibodyAnti-Ptb Domain Adapter Protein Ced-6 antibodyAnti-Protein Gulp antibodyAnti-GULP1 antibodyAnti-CED6 antibodyAnti-GULP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance