| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GULP1 |
| Gene ID: | 51454 |
| Uniprot ID: | GULP1_HUMAN |
| Immunogen Region: | 1-130 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human GULP1 (NP_057399.1). |
| Immunogen Sequence: | MNRAFSRKKDKTWMHTPEAL SKHFIPYNAKFLGSTEVEQP KGTEVVRDAVRKLKFARHIK KSEGQKIPKVELQISIYGVK ILEPKTKEVQHNCQLHRISF CADDKTDKRIFTFICKDSES NKHLCYVFDS |
| Tissue Specificity | Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary. |
| Function | May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6. |
| Protein Name | Ptb Domain-Containing Engulfment Adapter Protein 1Cell Death Protein 6 HomologPtb Domain Adapter Protein Ced-6Protein Gulp |
| Cellular Localisation | CytoplasmMay Associate With The Cytoplasmic Side Of The Plasma Membrane And Early Endosomes |
| Alternative Antibody Names | Anti-Ptb Domain-Containing Engulfment Adapter Protein 1 antibodyAnti-Cell Death Protein 6 Homolog antibodyAnti-Ptb Domain Adapter Protein Ced-6 antibodyAnti-Protein Gulp antibodyAnti-GULP1 antibodyAnti-CED6 antibodyAnti-GULP antibody |
Information sourced from Uniprot.org
