Anti-GUCY2D antibody (STJA0007642)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human GUCY2D
General Information
| Short Description | Rabbit polyclonal anti-Retinal guanylyl cyclase 1 for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GUCY2D |
| Gene ID | 3000 |
| Uniprot ID | GUC2D_HUMAN |
| Immunogen | Synthesized peptide derived from human GUCY2D |
| Specificity | This antibody detects endogenous levels of GUCY2D at Human, Rat |
Additional Info
| Function | Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane. |
| Protein Name | Retinal Guanylyl Cyclase 1Retgc-1Cg-EGuanylate Cyclase 2d - RetinalRod Outer Segment Membrane Guanylate CyclaseRos-Gc |
| Database Links | Reactome: R-HSA-2514859 |
| Cellular Localisation | Photoreceptor Outer Segment MembraneSingle-Pass Type I Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Retinal Guanylyl Cyclase 1 antibodyAnti-Retgc-1 antibodyAnti-Cg-E antibodyAnti-Guanylate Cyclase 2d - Retinal antibodyAnti-Rod Outer Segment Membrane Guanylate Cyclase antibodyAnti-Ros-Gc antibodyAnti-GUCY2D antibodyAnti-CORD6 antibodyAnti-GUC1A4 antibodyAnti-GUC2D antibodyAnti-RETGC antibodyAnti-RETGC1 antibody |
Information sourced from Uniprot.org