| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GTF3C4 |
| Gene ID: | 9329 |
| Uniprot ID: | TF3C4_HUMAN |
| Immunogen Region: | 583-822 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 583-822 of human GTF3C4 (NP_036336.2). |
| Immunogen Sequence: | ILYQSMQKTPSEALWKPTHE DSKILLVDSPGMGNADDEQQ EEGTSSKQVVKQGLQERSKE GDVEEPTDDSLPTTGDAGGR EPMEEKLLEIQGKIEAVEMH LTREHMKRVLGEVYLHTWIT ENTSIPTRGLCNFLMSDEEY DDRTARVLIGHISKKMNKQT FPEHCSLCKEILPFTDRKQA VCSNGHIWLRCFLTYQSCQS LIYRRCLLHDSIARHPAPED PDWIKRLLQSPCPFCDSPV |
| Function | Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box. |
| Protein Name | General Transcription Factor 3c Polypeptide 4Tf3c-DeltaTranscription Factor Iiic 90 Kda SubunitTfiiic 90 Kda SubunitTfiiic90Transcription Factor Iiic Subunit Delta |
| Database Links | Reactome: R-HSA-749476Reactome: R-HSA-76061Reactome: R-HSA-76066 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-General Transcription Factor 3c Polypeptide 4 antibodyAnti-Tf3c-Delta antibodyAnti-Transcription Factor Iiic 90 Kda Subunit antibodyAnti-Tfiiic 90 Kda Subunit antibodyAnti-Tfiiic90 antibodyAnti-Transcription Factor Iiic Subunit Delta antibodyAnti-GTF3C4 antibody |
Information sourced from Uniprot.org