| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-General Transcription Factor Ii-I Repeat Domain-Containing Protein 1 (660-890) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GTF2IRD1 |
| Gene ID: |
9569 |
| Uniprot ID: |
GT2D1_HUMAN |
| Immunogen Region: |
660-890 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 660-890 of human GTF2IRD1 (NP_057412.1). |
| Immunogen Sequence: |
SLGFSPPALPPERDSGDPLV DESLKRQGFQENYDARLSRI DIANTLREQVQDLFNKKYGE ALGIKYPVQVPYKRIKSNPG SVIIEGLPPGIPFRKPCTFG SQNLERILAVADKIKFTVTR PFQGLIPKPDEDDANRLGEK VILREQVKELFNEKYGEALG LNRPVLVPYKLIRDSPDAVE VTGLPDDIPFRNPNTYDIHR LEKILKAREHVRMVIINQLQ PFAEICNDAKV |
| Tissue Specificity | Highly expressed in adult skeletal muscle, heart, fibroblast, bone and fetal tissues. Expressed at lower levels in all other tissues tested. |
| Function | May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8. |
| Protein Name | General Transcription Factor Ii-I Repeat Domain-Containing Protein 1Gtf2i Repeat Domain-Containing Protein 1General Transcription Factor IiiMustrd1/BenMuscle Tfii-I Repeat Domain-Containing Protein 1Slow-Muscle-Fiber Enhancer-Binding ProteinUse B1-Binding ProteinWilliams-Beuren Syndrome Chromosomal Region 11 ProteinWilliams-Beuren Syndrome Chromosomal Region 12 Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-General Transcription Factor Ii-I Repeat Domain-Containing Protein 1 antibodyAnti-Gtf2i Repeat Domain-Containing Protein 1 antibodyAnti-General Transcription Factor Iii antibodyAnti-Mustrd1/Ben antibodyAnti-Muscle Tfii-I Repeat Domain-Containing Protein 1 antibodyAnti-Slow-Muscle-Fiber Enhancer-Binding Protein antibodyAnti-Use B1-Binding Protein antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 11 Protein antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 12 Protein antibodyAnti-GTF2IRD1 antibodyAnti-CREAM1 antibodyAnti-GTF3 antibodyAnti-MUSTRD1 antibodyAnti-RBAP2 antibodyAnti-WBSCR11 antibodyAnti-WBSCR12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
