Anti-GSTP1 antibody (1-210) (STJ27658)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GSTP1 (1-210) antibody for use in WB, IHC-P, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GSTP1 |
| Gene ID | 2950 |
| Uniprot ID | GSTP1_HUMAN |
| Immunogen Region | 1-210 |
| Immunogen Sequence | MPPYTVVYFPVRGRCAALRM LLADQGQSWKEEVVTVETWQ EGSLKASCLYGQLPKFQDGD LTLYQSNTILRHLGRTLGLY GKDQQEAALVDMVNDGVEDL RCKYISLIYTNYEAGKDDYV KALPGQLKPFETLLSQNQGG KTFIVGDQISFADYNLLDLL LIHEVLAPGCLDAFPLLSAY VGRLSARPKLKAFLASPEYV NLPINGNGKQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human GST3/GST3/GSTP1 (NP_000843.1). |
Additional Info
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration. |
| Protein Name | Glutathione S-Transferase PGst Class-PiGstp1-1 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-3299685Reactome: R-HSA-6798695Reactome: R-HSA-9753281 |
| Cellular Localisation | CytoplasmMitochondrionNucleusThe 83 N-Terminal Amino Acids Function As Un Uncleaved Transit PeptideAnd Arginine Residues Within It Are Crucial For Mitochondrial Localization |
| Alternative Antibody Names | Anti-Glutathione S-Transferase P antibodyAnti-Gst Class-Pi antibodyAnti-Gstp1-1 antibodyAnti-GSTP1 antibodyAnti-FAEES3 antibodyAnti-GST3 antibody |
Information sourced from Uniprot.org