| Tissue Specificity | Ubiquitous. Highest expression in liver, pancreas, skeletal muscle, spleen, thymus, colon, blood leukocyte and heart. Lowest expression in brain, placenta and lung. |
| Function | Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Also has glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. |
| Protein Name | Glutathione S-Transferase Omega-1Gsto-1Glutathione S-Transferase Omega 1-1Gsto 1-1Glutathione-Dependent Dehydroascorbate ReductaseMonomethylarsonic Acid ReductaseMma(V ReductaseS-(Phenacylglutathione ReductaseSpg-R |
| Database Links | Reactome: R-HSA-156581Reactome: R-HSA-156590Reactome: R-HSA-196836Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Glutathione S-Transferase Omega-1 antibodyAnti-Gsto-1 antibodyAnti-Glutathione S-Transferase Omega 1-1 antibodyAnti-Gsto 1-1 antibodyAnti-Glutathione-Dependent Dehydroascorbate Reductase antibodyAnti-Monomethylarsonic Acid Reductase antibodyAnti-Mma(V Reductase antibodyAnti-S-(Phenacylglutathione Reductase antibodyAnti-Spg-R antibodyAnti-GSTO1 antibodyAnti-GSTTLP28 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and GSTO1 knockout (KO) 293T cells, using [KO Validated] GSTO1 Rabbit polyclonal antibody (STJ11100768) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89705/358188/STJ11100768_1__90554.1713122502.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and GSTO1 knockout (KO) 293T cells, using [KO Validated] GSTO1 Rabbit polyclonal antibody (STJ11100768) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.")
