| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GSTA3 |
| Gene ID: | 2940 |
| Uniprot ID: | GSTA3_HUMAN |
| Immunogen Region: | 1-222 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human GSTA3 (NP_000838.3). |
| Immunogen Sequence: | MAGKPKLHYFNGRGRMEPIR WLLAAAGVEFEEKFIGSAED LGKLRNDGSLMFQQVPMVEI DGMKLVQTRAILNYIASKYN LYGKDIKERALIDMYTEGMA DLNEMILLLPLCRPEEKDAK IALIKEKTKSRYFPAFEKVL QSHGQDYLVGNKLSRADISL VELLYYVEELDSSLISNFPL LKALKTRISNLPTVKKFLQP GSPRKPPADAKALEEARKIF RF |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones. Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)-pregnene-3,20-dione, precursors to testosterone and progesterone, respectively. Has substantial activity toward aflatoxin B1-8,9-epoxide. |
| Protein Name | Glutathione S-Transferase A3Gst Class-Alpha Member 3Glutathione S-Transferase A3-3 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-9818027 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Glutathione S-Transferase A3 antibodyAnti-Gst Class-Alpha Member 3 antibodyAnti-Glutathione S-Transferase A3-3 antibodyAnti-GSTA3 antibody |
Information sourced from Uniprot.org