| Host: | Rabbit |
| Applications: | WB/IHC-F/IHC-P/ICC/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-GST3 for use in WB, IHC-F, IHC-P, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R09-4G8 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification: | Affinity Purified |
| Concentration: | 0.3 mg/mL |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | GSTP1 |
| Gene ID: | 2950 |
| Uniprot ID: | GSTP1_HUMAN |
| Immunogen: | A synthetic peptide of human GST3/GST pi |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration. |
| Protein Name | Glutathione S-Transferase PGst Class-PiGstp1-1 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-3299685Reactome: R-HSA-6798695Reactome: R-HSA-9753281 |
| Cellular Localisation | CytoplasmMitochondrionNucleusThe 83 N-Terminal Amino Acids Function As Un Uncleaved Transit PeptideAnd Arginine Residues Within It Are Crucial For Mitochondrial Localization |
| Alternative Antibody Names | Anti-Glutathione S-Transferase P antibodyAnti-Gst Class-Pi antibodyAnti-Gstp1-1 antibodyAnti-GSTP1 antibodyAnti-FAEES3 antibodyAnti-GST3 antibody |
Information sourced from Uniprot.org
