| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GRIN2D (330-480) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GRIN2D |
| Gene ID: |
2906 |
| Uniprot ID: |
NMDE4_HUMAN |
| Immunogen Region: |
330-480 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 330-480 of human GRIN2D (NP_000827.2). |
| Immunogen Sequence: |
GAQALLRDYGFLPELGHDCR AQNRTHRGESLHRYFMNITW DNRDYSFNEDGFLVNPSLVV ISLTRDRTWEVVGSWEQQTL RLKYPLWSRYGRFLQPVDDT QHLTVATLEERPFVIVEPAD PISGTCIRDSVPCRSQLNRT HSPPPDAPRPE |
| Function | Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. |
| Protein Name | Glutamate Receptor Ionotropic - Nmda 2dGlun2dEb11Glutamate Nmda Receptor Subunit Epsilon-4N-Methyl D-Aspartate Receptor Subtype 2dNmdar2dNr2d |
| Database Links | Reactome: R-HSA-438066Reactome: R-HSA-442982Reactome: R-HSA-5673001Reactome: R-HSA-6794361Reactome: R-HSA-8849932Reactome: R-HSA-9609736Reactome: R-HSA-9617324Reactome: R-HSA-9620244 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Glutamate Receptor Ionotropic - Nmda 2d antibodyAnti-Glun2d antibodyAnti-Eb11 antibodyAnti-Glutamate Nmda Receptor Subunit Epsilon-4 antibodyAnti-N-Methyl D-Aspartate Receptor Subtype 2d antibodyAnti-Nmdar2d antibodyAnti-Nr2d antibodyAnti-GRIN2D antibodyAnti-GluN2D antibodyAnti-NMDAR2D antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
