| Function | Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In association with GRIK2, involved in presynaptic facilitation of glutamate release at hippocampal mossy fiber synapses. |
| Protein Name | Glutamate Receptor Ionotropic - Kainate 3Gluk3Excitatory Amino Acid Receptor 5Eaa5Glutamate Receptor 7Glur-7Glur7 |
| Database Links | Reactome: R-HSA-451308Reactome: R-HSA-500657 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Glutamate Receptor Ionotropic - Kainate 3 antibodyAnti-Gluk3 antibodyAnti-Excitatory Amino Acid Receptor 5 antibodyAnti-Eaa5 antibodyAnti-Glutamate Receptor 7 antibodyAnti-Glur-7 antibodyAnti-Glur7 antibodyAnti-GRIK3 antibodyAnti-GLUR7 antibody |
Information sourced from Uniprot.org
