| Function | Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Isoform 2: Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. |
| Protein Name | Glutamate Receptor Ionotropic - Kainate 1Gluk1Excitatory Amino Acid Receptor 3Eaa3Glutamate Receptor 5Glur-5Glur5 |
| Database Links | Reactome: R-HSA-451307Reactome: R-HSA-451308 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Glutamate Receptor Ionotropic - Kainate 1 antibodyAnti-Gluk1 antibodyAnti-Excitatory Amino Acid Receptor 3 antibodyAnti-Eaa3 antibodyAnti-Glutamate Receptor 5 antibodyAnti-Glur-5 antibodyAnti-Glur5 antibodyAnti-GRIK1 antibodyAnti-GLUR5 antibody |
Information sourced from Uniprot.org
