| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
GRIK1 |
| Gene ID: |
2897 |
| Uniprot ID: |
GRIK1_HUMAN |
| Immunogen Region: |
859-918 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 859-918 of human GRIK1 (NP_000821.1). |
| Immunogen Sequence: |
YKSRKNNDIEQAFCFFYGLQ CKQTHPTNSTSGTTLSTDLE CGKLIREERGIRKQSSVHTV |
| Function | Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Isoform 2: Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. |
| Protein Name | Glutamate Receptor Ionotropic - Kainate 1Gluk1Excitatory Amino Acid Receptor 3Eaa3Glutamate Receptor 5Glur-5Glur5 |
| Database Links | Reactome: R-HSA-451307Reactome: R-HSA-451308 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Glutamate Receptor Ionotropic - Kainate 1 antibodyAnti-Gluk1 antibodyAnti-Excitatory Amino Acid Receptor 3 antibodyAnti-Eaa3 antibodyAnti-Glutamate Receptor 5 antibodyAnti-Glur-5 antibodyAnti-Glur5 antibodyAnti-GRIK1 antibodyAnti-GLUR5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
