Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Glutamate receptor ionotropic, kainate 1 (10-59 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GRIK1 |
Gene ID: |
2897 |
Uniprot ID: |
GRIK1_HUMAN |
Immunogen Region: |
10-59 aa |
Specificity: |
GluR-5 Polyclonal Antibody detects endogenous levels of GluR-5 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human GluR5 at the amino acid range 10-59 |
Function | Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. |
Protein Name | Glutamate Receptor Ionotropic - Kainate 1Gluk1Excitatory Amino Acid Receptor 3Eaa3Glutamate Receptor 5Glur-5Glur5 |
Database Links | Reactome: R-HSA-451307Reactome: R-HSA-451308 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell Membrane |
Alternative Antibody Names | Anti-Glutamate Receptor Ionotropic - Kainate 1 antibodyAnti-Gluk1 antibodyAnti-Excitatory Amino Acid Receptor 3 antibodyAnti-Eaa3 antibodyAnti-Glutamate Receptor 5 antibodyAnti-Glur-5 antibodyAnti-Glur5 antibodyAnti-GRIK1 antibodyAnti-GLUR5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance