• Western blot analysis of extracts of various cell lines, using GRID1 antibody (STJ110317) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
  • Immunofluorescence analysis of L929 cells using GRID1 Rabbit polyclonal antibody (STJ110317) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of L929 cells using GRID1 rabbit polyclonal antibody (STJ110317) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using GRID1 antibody (STJ110317) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-GRID1 antibody (880-1009) (STJ110317)

SKU:
STJ110317

£112.50 - £524.50
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GRID1
Gene ID: 2894
Uniprot ID: GRID1_HUMAN
Immunogen Region: 880-1009
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 880-1009 of human GRID1 (NP_060021.1).
Immunogen Sequence: MNSLMDEDIAHKQISPASIE LSALEMGGLAPTQTLEPTRE YQNTQLSVSTFLPEQSSHGT SRTLSSGPSSNLPLPLSSSA TMPSMQCKHRSPNGGLFRQS PVKTPIPMSFQPVPGGVLPE ALDTSHGTSI
Function Member of the ionotropic glutamate receptor family, which plays a crucial role in synaptic organization and signal transduction in the central nervous system. Although it shares structural features with ionotropic glutamate receptors, does not bind glutamate as a primary ligand. Instead, forms trans-synaptic adhesion complexes with presynaptic neurexins and cerebellins, regulating NMDA and AMPA receptor activity and influencing synaptic plasticity through signal transduction. In the presence of neurexins and cerebellins, forms cation-selective channels that are proposed to be gated by glycine and D-serine. However, recent research disputes this ligand-gated cation channel activity. Cation-selective ion channel can be triggered by GRM1 in dopaminergic neurons. Also acts as a receptor for GABA, modulating inhibitory synaptic plasticity through non-ionotropic mechanisms.
Protein Name Glutamate Receptor Ionotropic - Delta-1
Glud1
Glur Delta-1 Subunit
Cellular Localisation Postsynaptic Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Glutamate Receptor Ionotropic - Delta-1 antibody
Anti-Glud1 antibody
Anti-Glur Delta-1 Subunit antibody
Anti-GRID1 antibody
Anti-KIAA1220 antibody

Information sourced from Uniprot.org

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