| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-GRAM domain-containing protein 4 (304-354 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GRAMD4 |
| Gene ID: | 23151 |
| Uniprot ID: | GRAM4_HUMAN |
| Immunogen Region: | 304-354 aa |
| Specificity: | This antibody detects endogenous levels of GRAM4 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human GRAM4 at the amino acid range 304-354 |
| Function | Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response. |
| Protein Name | Gram Domain-Containing Protein 4Death-Inducing Protein |
| Cellular Localisation | Mitochondrion MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum MembraneColocalizes With Cox4i1 |
| Alternative Antibody Names | Anti-Gram Domain-Containing Protein 4 antibodyAnti-Death-Inducing Protein antibodyAnti-GRAMD4 antibodyAnti-DIP antibodyAnti-KIAA0767 antibody |
Information sourced from Uniprot.org