Tissue Specificity | Mostly in liver and gastrointestinal tract, not found in heart or kidney. |
Function | Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. Cannot reduce phosphatidycholine hydroperoxide. |
Protein Name | Glutathione Peroxidase 2Gpx-2Gshpx-2Gastrointestinal Glutathione PeroxidaseGlutathione Peroxidase-GastrointestinalGpx-GiGshpx-GiGlutathione Peroxidase-Related Protein 2Gprp-2Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2 |
Database Links | Reactome: R-HSA-2142688Reactome: R-HSA-2142712Reactome: R-HSA-2142770Reactome: R-HSA-3299685Reactome: R-HSA-5628897 |
Cellular Localisation | CytoplasmCytosol |
Alternative Antibody Names | Anti-Glutathione Peroxidase 2 antibodyAnti-Gpx-2 antibodyAnti-Gshpx-2 antibodyAnti-Gastrointestinal Glutathione Peroxidase antibodyAnti-Glutathione Peroxidase-Gastrointestinal antibodyAnti-Gpx-Gi antibodyAnti-Gshpx-Gi antibodyAnti-Glutathione Peroxidase-Related Protein 2 antibodyAnti-Gprp-2 antibodyAnti-Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2 antibodyAnti-GPX2 antibody |
Information sourced from Uniprot.org