• Immunohistochemistry analysis of GPX2 in paraffin-embedded mouse stomach using GPX2 Rabbit polyclonal antibody (STJ118444) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of GPX2 in paraffin-embedded rat stomach using GPX2 Rabbit polyclonal antibody (STJ118444) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of GPX2 in paraffin-embedded human colon carcinoma using GPX2 Rabbit polyclonal antibody (STJ118444) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of various lysates using GPX2 Rabbit polyclonal antibody (STJ118444) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-GPX2 antibody (100-180) (STJ118444)

SKU:
STJ118444

£112.50 - £524.50
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GPX2
Gene ID: 2877
Uniprot ID: GPX2_HUMAN
Immunogen Region: 100-180
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 100-180 of human GPX2 (NP_002074.2).
Immunogen Sequence: TLVQKCEVNGQNEHPVFAYL KDKLPYPYDDPFSLMTDPKL IIWSPVRRSDVAWNFEKFLI GPEGEPFRRYSRTFPTINIE P
Tissue Specificity Mostly in liver and gastrointestinal tract, not found in heart or kidney.
Function Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. Cannot reduce phosphatidycholine hydroperoxide.
Protein Name Glutathione Peroxidase 2
Gpx-2
Gshpx-2
Gastrointestinal Glutathione Peroxidase
Glutathione Peroxidase-Gastrointestinal
Gpx-Gi
Gshpx-Gi
Glutathione Peroxidase-Related Protein 2
Gprp-2
Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2
Database Links Reactome: R-HSA-2142688
Reactome: R-HSA-2142712
Reactome: R-HSA-2142770
Reactome: R-HSA-3299685
Reactome: R-HSA-5628897
Cellular Localisation Cytoplasm
Cytosol
Alternative Antibody Names Anti-Glutathione Peroxidase 2 antibody
Anti-Gpx-2 antibody
Anti-Gshpx-2 antibody
Anti-Gastrointestinal Glutathione Peroxidase antibody
Anti-Glutathione Peroxidase-Gastrointestinal antibody
Anti-Gpx-Gi antibody
Anti-Gshpx-Gi antibody
Anti-Glutathione Peroxidase-Related Protein 2 antibody
Anti-Gprp-2 antibody
Anti-Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2 antibody
Anti-GPX2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance