| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GPRIN1 (1-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GPRIN1 |
| Gene ID: |
114787 |
| Uniprot ID: |
GRIN1_HUMAN |
| Immunogen Region: |
1-300 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GPRIN1 (NP_443131.2). |
| Immunogen Sequence: |
MDTAEDPAWLQLLQKDSSPP GPRPTAFFCPQDGSLGAGSS AMRDYCPSQQKASPAPPRHT PDQSPGMESRHRSPSGAGEG ASCSDGPRGSLACPSPTCFS PQESPSKETLEAHGASISGT PEATTSGKPEPVSSVKTEPK SSDDRNPMFLEKMDFKSSKQ ADSTSIGKEDPGSSRKADPM FTGKAEPEILGKGDPVAPGR MDPMTVRKEDLGSLGKVDPL CSSKTYTVSPRKEDPGSLR |
| Tissue Specificity | Widely expressed in the central nervous system, with highest levels in spinal cord. |
| Post Translational Modifications | Palmitoylation on Cys-999 and/or Cys-1000 is required for membrane targeting. |
| Function | May be involved in neurite outgrowth. |
| Protein Name | G Protein-Regulated Inducer Of Neurite Outgrowth 1Grin1 |
| Database Links | Reactome: R-HSA-9022699 |
| Cellular Localisation | Cell MembraneLipid-AnchorCell ProjectionGrowth ConeHighly Enriched In Growth Cone |
| Alternative Antibody Names | Anti-G Protein-Regulated Inducer Of Neurite Outgrowth 1 antibodyAnti-Grin1 antibodyAnti-GPRIN1 antibodyAnti-KIAA1893 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and BUB1 knockout (KO) HeLa cells, using [KO Validated] BUB1 Rabbit polyclonal antibody (STJ11100026) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89098/357557/STJ11100026_1__69013.1713121681.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and BUB1 knockout (KO) HeLa cells, using [KO Validated] BUB1 Rabbit polyclonal antibody (STJ11100026) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.")
