| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPRIN1 |
| Gene ID: | 114787 |
| Uniprot ID: | GRIN1_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GPRIN1 (NP_443131.2). |
| Immunogen Sequence: | MDTAEDPAWLQLLQKDSSPP GPRPTAFFCPQDGSLGAGSS AMRDYCPSQQKASPAPPRHT PDQSPGMESRHRSPSGAGEG ASCSDGPRGSLACPSPTCFS PQESPSKETLEAHGASISGT PEATTSGKPEPVSSVKTEPK SSDDRNPMFLEKMDFKSSKQ ADSTSIGKEDPGSSRKADPM FTGKAEPEILGKGDPVAPGR MDPMTVRKEDLGSLGKVDPL CSSKTYTVSPRKEDPGSLR |
| Tissue Specificity | Widely expressed in the central nervous system, with highest levels in spinal cord. |
| Post Translational Modifications | Palmitoylation on Cys-999 and/or Cys-1000 is required for membrane targeting. |
| Function | May be involved in neurite outgrowth. |
| Protein Name | G Protein-Regulated Inducer Of Neurite Outgrowth 1Grin1 |
| Database Links | Reactome: R-HSA-9022699 |
| Cellular Localisation | Cell MembraneLipid-AnchorCell ProjectionGrowth ConeHighly Enriched In Growth Cone |
| Alternative Antibody Names | Anti-G Protein-Regulated Inducer Of Neurite Outgrowth 1 antibodyAnti-Grin1 antibodyAnti-GPRIN1 antibodyAnti-KIAA1893 antibody |
Information sourced from Uniprot.org