| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-GPR83 (59-71) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 48kDa band observed in Human, Mouse and Rat Brain lysates (calculated MW of 48.3kDa according to Human NP_057624.3 and 48.0kDa according to Rat NP_536336.1). Recommended concentr |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | GPR83 |
| Gene ID: | 10888 |
| Uniprot ID: | GPR83_HUMAN |
| Immunogen Region: | 59-71 |
| Accession Number: | NP_057624.3 |
| Specificity: | The immunizing peptide represents part of an extracellular domain. |
| Immunogen Sequence: | RRYGAESQNPTVK |
| Function | G-protein coupled receptor for PEN, a neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N). Acts through a G(i)- and G(q)-alpha-alpha-mediated pathway in response to PEN. Plays a role in food intake and body weight regulation. May contribute to the regulation of anxiety-related behaviors. |
| Protein Name | G-Protein Coupled Receptor 83G-Protein Coupled Receptor 72 |
| Database Links | Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinColocalizes With Gpr171 In The Paraventricular NucleusColocalizes With The Ghrelin Receptor Ghsr1a In The Hypothalamus |
| Alternative Antibody Names | Anti-G-Protein Coupled Receptor 83 antibodyAnti-G-Protein Coupled Receptor 72 antibodyAnti-GPR83 antibodyAnti-GPR72 antibodyAnti-JP05 antibodyAnti-KIAA1540 antibody |
Information sourced from Uniprot.org