| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-G-protein coupled receptor 83 (361-410 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPR83 |
| Gene ID: | 10888 |
| Uniprot ID: | GPR83_HUMAN |
| Immunogen Region: | 361-410 aa |
| Specificity: | GPR83 Polyclonal Antibody detects endogenous levels of GPR83 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human GPR83 at the amino acid range 361-410 |
| Function | G-protein coupled receptor for PEN, a neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N). Acts through a G(i)- and G(q)-alpha-alpha-mediated pathway in response to PEN. Plays a role in food intake and body weight regulation. May contribute to the regulation of anxiety-related behaviors. |
| Protein Name | G-Protein Coupled Receptor 83G-Protein Coupled Receptor 72 |
| Database Links | Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinColocalizes With Gpr171 In The Paraventricular NucleusColocalizes With The Ghrelin Receptor Ghsr1a In The Hypothalamus |
| Alternative Antibody Names | Anti-G-Protein Coupled Receptor 83 antibodyAnti-G-Protein Coupled Receptor 72 antibodyAnti-GPR83 antibodyAnti-GPR72 antibodyAnti-JP05 antibodyAnti-KIAA1540 antibody |
Information sourced from Uniprot.org