• Western blot analysis of the lysates from HT-29 cells using GPR37 antibody.
  • Western blot analysis of GPR37 Antibody. The lane on the right is blocked with the GPR37 peptide.

Anti-GPR37 antibody (211-260 aa) (STJ93381)

SKU:
STJ93381

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Prosaposin receptor GPR37 (211-260 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GPR37
Gene ID: 2861
Uniprot ID: GPR37_HUMAN
Immunogen Region: 211-260 aa
Specificity: GPR37 Polyclonal Antibody detects endogenous levels of GPR37 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human GPR37 at the amino acid range 211-260
Post Translational Modifications Ubiquitinated by PRKN in the presence of UBE2E1 and UBE2L3 in the endoplasmic reticulum. The unfolded form is specifically ubiquitinated by SYVN1, which promotes its proteasomal degradation and prevents neuronal cell death.
Function Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade.
Protein Name Prosaposin Receptor Gpr37
Endothelin B Receptor-Like Protein 1
Etbr-Lp-1
G-Protein Coupled Receptor 37
Parkin-Associated Endothelin Receptor-Like Receptor
Paelr
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Prosaposin Receptor Gpr37 antibody
Anti-Endothelin B Receptor-Like Protein 1 antibody
Anti-Etbr-Lp-1 antibody
Anti-G-Protein Coupled Receptor 37 antibody
Anti-Parkin-Associated Endothelin Receptor-Like Receptor antibody
Anti-Paelr antibody
Anti-GPR37 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance