| Short Description : | Rabbit polyclonal anti-Probable G-protein coupled receptor 19 (361-410 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPR19 |
| Gene ID: | 2842 |
| Uniprot ID: | GPR19_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human GPR19 at the amino acid range 361-410 |
| Immunogen Region: | 361-410 aa |
| Specificity: | GPR19 Polyclonal Antibody detects endogenous levels of GPR19 protein. |
| Function | G-protein coupled receptor that plays a role in the regulation of circadian rhythms and energy metabolism. Participates in maintaining proper circadian gene expression in the suprachiasmatic nucleus (SCN), the locus of the master circadian clock in the brain. May function as a coordinator of aging-associated metabolic dysfunction, stress response, DNA integrity management, and eventual senescence. Upon binding to adropin, modulates mitochondrial energy metabolism via the p44/42-PDK4 signaling pathway, influencing pyruvate dehydrogenase activity. |
| Protein Name | Probable G-Protein Coupled Receptor 19Gpr-Nga |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Probable G-Protein Coupled Receptor 19 antibodyAnti-Gpr-Nga antibodyAnti-GPR19 antibody |
Information sourced from Uniprot.org
