| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPR135 |
| Gene ID: | 64582 |
| Uniprot ID: | GP135_HUMAN |
| Immunogen Region: | 375-494 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 375-494 of human GPR135 (NP_072093.2). |
| Immunogen Sequence: | LTWANGAINPVIYAIRNPNI SMLLGRNREEGYRTRNVDAF LPSQGPGLQARSRSRLRNRY ANRLGACNRMSSSNPASGVA GDVAMWARKNPVVLFCREGP PEPVTAVTKQPKSEAGDTSL |
| Function | Orphan receptor. Has spontaneous activity for beta-arrestin recruitment. Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization. |
| Protein Name | G-Protein Coupled Receptor 135 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Endosome Membrane Colocalizes With Arrb2/Beta-Arrestin-2 In The Endosome |
| Alternative Antibody Names | Anti-G-Protein Coupled Receptor 135 antibody Anti-GPR135 antibody |
Information sourced from Uniprot.org