| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GPR135 (375-494) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GPR135 |
| Gene ID: |
64582 |
| Uniprot ID: |
GP135_HUMAN |
| Immunogen Region: |
375-494 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 375-494 of human GPR135 (NP_072093.2). |
| Immunogen Sequence: |
LTWANGAINPVIYAIRNPNI SMLLGRNREEGYRTRNVDAF LPSQGPGLQARSRSRLRNRY ANRLGACNRMSSSNPASGVA GDVAMWARKNPVVLFCREGP PEPVTAVTKQPKSEAGDTSL |
| Function | Orphan receptor. Has spontaneous activity for beta-arrestin recruitment. Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization. |
| Protein Name | G-Protein Coupled Receptor 135 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEndosome MembraneColocalizes With Arrb2/Beta-Arrestin-2 In The Endosome |
| Alternative Antibody Names | Anti-G-Protein Coupled Receptor 135 antibodyAnti-GPR135 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
