| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GPR108 (33-260) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:5000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GPR108 |
| Gene ID: |
56927 |
| Uniprot ID: |
GP108_HUMAN |
| Immunogen Region: |
33-260 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 33-260 of human GPR108 (NP_001073921.1). |
| Immunogen Sequence: |
RIHQLALTGEKRADIQLNSF GFYTNGSLEVELSVLRLGLR EAEEKSLLVGFSLSRVRSGR VRSYSTRDFQDCPLQKNSSS FLVLFLINTKDLQVQVRKYG EQKTLFIFPGLLPEAPSKPG LPKPQATVPRKVDGGGTSAA SKPKSTPAVIQGPSGKDKDL VLGLSHLNNSYNFSFHVVIG SQAEEGQYSLNFHNCNNSVP GKEHPFDITVMIREKNPDGF LSAAEMPL |
| Function | May play a role in intracellular immune modulation by activating NF-kappaB response and attenuating Toll-like-receptor response. (Microbial infection) Plays an essential function in adeno-associated virus (AAV) transduction across multiple serotypes except AAV5. May play a critical role in mediating the endosomal virus escape or in the AAV virions trafficking from endosomes to the nucleus. |
| Protein Name | Protein Gpr108Lung Seven Transmembrane Receptor 2 |
| Cellular Localisation | Golgi ApparatusCis-Golgi Network MembraneMulti-Pass Membrane ProteinTrans-Golgi Network MembraneGolgi Apparatus MembraneColocalizes With Tlr3-7-4And -9 |
| Alternative Antibody Names | Anti-Protein Gpr108 antibodyAnti-Lung Seven Transmembrane Receptor 2 antibodyAnti-GPR108 antibodyAnti-LUSTR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
