| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPR108 |
| Gene ID: | 56927 |
| Uniprot ID: | GP108_HUMAN |
| Immunogen Region: | 33-260 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 33-260 of human GPR108 (NP_001073921.1). |
| Immunogen Sequence: | RIHQLALTGEKRADIQLNSF GFYTNGSLEVELSVLRLGLR EAEEKSLLVGFSLSRVRSGR VRSYSTRDFQDCPLQKNSSS FLVLFLINTKDLQVQVRKYG EQKTLFIFPGLLPEAPSKPG LPKPQATVPRKVDGGGTSAA SKPKSTPAVIQGPSGKDKDL VLGLSHLNNSYNFSFHVVIG SQAEEGQYSLNFHNCNNSVP GKEHPFDITVMIREKNPDGF LSAAEMPL |
| Function | May play a role in intracellular immune modulation by activating NF-kappaB response and attenuating Toll-like-receptor response. (Microbial infection) Plays an essential function in adeno-associated virus (AAV) transduction across multiple serotypes except AAV5. May play a critical role in mediating the endosomal virus escape or in the AAV virions trafficking from endosomes to the nucleus. |
| Protein Name | Protein Gpr108Lung Seven Transmembrane Receptor 2 |
| Cellular Localisation | Golgi ApparatusCis-Golgi Network MembraneMulti-Pass Membrane ProteinTrans-Golgi Network MembraneGolgi Apparatus MembraneColocalizes With Tlr3-7-4And -9 |
| Alternative Antibody Names | Anti-Protein Gpr108 antibodyAnti-Lung Seven Transmembrane Receptor 2 antibodyAnti-GPR108 antibodyAnti-LUSTR2 antibody |
Information sourced from Uniprot.org