| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-GPI/Neuroleukin (81-93) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 60kDa band observed in Human Heart lysates and approx 55kDa observed in lysates of cell lines HeLa, A431, A549, MCF7, Jurkat and K562 (calculated MW of 63.1kDa according to NP_ |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
GPI |
| Gene ID: |
2821 |
| Uniprot ID: |
G6PI_HUMAN |
| Immunogen Region: |
81-93 |
| Accession Number: |
NP_000166.2 |
| Immunogen Sequence: |
RERMFNGEKINYT |
| Function | In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. |
| Protein Name | Glucose-6-Phosphate IsomeraseGpiAutocrine Motility FactorAmfNeuroleukinNlkPhosphoglucose IsomerasePgiPhosphohexose IsomerasePhiSperm Antigen 36Sa-36 |
| Database Links | Reactome: R-HSA-5628897Reactome: R-HSA-6798695Reactome: R-HSA-70171Reactome: R-HSA-70263 |
| Cellular Localisation | CytoplasmSecreted |
| Alternative Antibody Names | Anti-Glucose-6-Phosphate Isomerase antibodyAnti-Gpi antibodyAnti-Autocrine Motility Factor antibodyAnti-Amf antibodyAnti-Neuroleukin antibodyAnti-Nlk antibodyAnti-Phosphoglucose Isomerase antibodyAnti-Pgi antibodyAnti-Phosphohexose Isomerase antibodyAnti-Phi antibodyAnti-Sperm Antigen 36 antibodyAnti-Sa-36 antibodyAnti-GPI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
