| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-G-protein coupled bile acid receptor 1 (11-60 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPBAR1 |
| Gene ID: | 151306 |
| Uniprot ID: | GPBAR_HUMAN |
| Immunogen Region: | 11-60 aa |
| Specificity: | TGR5 Polyclonal Antibody detects endogenous levels of TGR5 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human GPBAR at the amino acid range 11-60 |
| Function | Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. |
| Protein Name | G-Protein Coupled Bile Acid Receptor 1G-Protein Coupled Receptor Gpcr19Hgpcr19Membrane-Type Receptor For Bile AcidsM-BarHbg37Bg37 |
| Database Links | Reactome: R-HSA-373076Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-G-Protein Coupled Bile Acid Receptor 1 antibodyAnti-G-Protein Coupled Receptor Gpcr19 antibodyAnti-Hgpcr19 antibodyAnti-Membrane-Type Receptor For Bile Acids antibodyAnti-M-Bar antibodyAnti-Hbg37 antibodyAnti-Bg37 antibodyAnti-GPBAR1 antibodyAnti-TGR5 antibody |
Information sourced from Uniprot.org