| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Glutathione peroxidase 2 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 24kDa band observed in Human Liver lysates (calculated MW of 21.9kDa according to NP_002074.2). Recommended concentration: 0.5-2µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | GPX2 |
| Gene ID: | 2877 |
| Uniprot ID: | GPX2_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_002074.2 |
| Immunogen Sequence: | SLDGEKVDFN |
| Function | Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. Cannot reduce phosphatidycholine hydroperoxide. |
| Protein Name | Glutathione Peroxidase 2Gpx-2Gshpx-2Gastrointestinal Glutathione PeroxidaseGlutathione Peroxidase-GastrointestinalGpx-GiGshpx-GiGlutathione Peroxidase-Related Protein 2Gprp-2Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2 |
| Database Links | Reactome: R-HSA-2142688Reactome: R-HSA-2142712Reactome: R-HSA-2142770Reactome: R-HSA-3299685Reactome: R-HSA-5628897 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Glutathione Peroxidase 2 antibodyAnti-Gpx-2 antibodyAnti-Gshpx-2 antibodyAnti-Gastrointestinal Glutathione Peroxidase antibodyAnti-Glutathione Peroxidase-Gastrointestinal antibodyAnti-Gpx-Gi antibodyAnti-Gshpx-Gi antibodyAnti-Glutathione Peroxidase-Related Protein 2 antibodyAnti-Gprp-2 antibodyAnti-Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2 antibodyAnti-GPX2 antibody |
Information sourced from Uniprot.org
