| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-GLuR5/GRIK1 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
IHC-3.75µg/mlELISA-antibody detection limit dilution 1:8000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
GRIK1 |
| Gene ID: |
2897 |
| Uniprot ID: |
GRIK1_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_000821.1; NP_783300.1 |
| Specificity: |
This antibody is expected to recognise both reported isoforms according to NP_000821.1 and NP_783300.1. |
| Immunogen Sequence: |
QCKQTHPTNSTS |
| Function | Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. |
| Protein Name | Glutamate Receptor Ionotropic - Kainate 1Gluk1Excitatory Amino Acid Receptor 3Eaa3Glutamate Receptor 5Glur-5Glur5 |
| Database Links | Reactome: R-HSA-451307Reactome: R-HSA-451308 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Glutamate Receptor Ionotropic - Kainate 1 antibodyAnti-Gluk1 antibodyAnti-Excitatory Amino Acid Receptor 3 antibodyAnti-Eaa3 antibodyAnti-Glutamate Receptor 5 antibodyAnti-Glur-5 antibodyAnti-Glur5 antibodyAnti-GRIK1 antibodyAnti-GLUR5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
