| Host: | Rabbit |
| Applications: | ELISA/IHC/IP/WB |
| Reactivity: | Human/Monkey/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Glucose-6-Phosphate, catalytic subunit (80-130) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.55-0.65 µg/µl |
| Dilution Range: | WB: 1:500ELISA: 1:10, 000IP: 1:10, 000 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | G6pc2 |
| Gene ID: | 14378 |
| Uniprot ID: | G6PC2_MOUSE |
| Immunogen Region: | 80-130 |
| Immunogen: | Synthetic peptide taken within amino acid region 80-130 on G6PC2 protein, and common in larger variant of glucose 6 phosphatase. |
| Tissue Specificity | Specifically expressed in pancreatic islet cells, in particular those of beta-cell origin. Not detected in testis, kidney, muscle, liver, lung, spleen, brain, pituitary, gastric fundus or heart. |
| Post Translational Modifications | N-glycosylated.the non-glycosylated form is more unstable and is degraded through the proteasome. |
| Function | May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis. |
| Protein Name | Glucose-6-Phosphatase 2G-6-Pase 2G6pase 2Islet-Specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein |
| Database Links | Reactome: R-MMU-70263 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Glucose-6-Phosphatase 2 antibodyAnti-G-6-Pase 2 antibodyAnti-G6pase 2 antibodyAnti-Islet-Specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein antibodyAnti-G6pc2 antibodyAnti-Igrp antibody |
Information sourced from Uniprot.org
