Anti-GLS2 antibody (STJA0009789)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human GLS2
General Information
| Short Description | Rabbit polyclonal anti-Glutaminase liver isoform, mitochondrial for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GLS2 |
| Gene ID | 27165 |
| Uniprot ID | GLSL_HUMAN |
| Immunogen | Synthesized peptide derived from human GLS2 |
| Specificity | This antibody detects endogenous levels of GLS2 at Human, Mouse, Rat |
Additional Info
| Function | Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation. |
| Protein Name | Glutaminase Liver Isoform - MitochondrialGlsL-GlutaminaseL-Glutamine Amidohydrolase |
| Database Links | Reactome: R-HSA-210500Reactome: R-HSA-5628897Reactome: R-HSA-8964539 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Glutaminase Liver Isoform - Mitochondrial antibodyAnti-Gls antibodyAnti-L-Glutaminase antibodyAnti-L-Glutamine Amidohydrolase antibodyAnti-GLS2 antibodyAnti-GA antibody |
Information sourced from Uniprot.org