| Host: |
Rabbit |
| Applications: |
ELISA/IHC/IP/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GIRK1 (420-470) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Biotin |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.60-0.65 µg/µl |
| Dilution Range: |
WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:50-1:150 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Kcnj3 |
| Gene ID: |
50599 |
| Uniprot ID: |
KCNJ3_RAT |
| Immunogen Region: |
420-470 |
| Immunogen: |
Synthetic peptide taken within amino acid region 420-470 rat GIRK1 protein. |
| Function | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat. |
| Protein Name | G Protein-Activated Inward Rectifier Potassium Channel 1Girk-1Inward Rectifier K(+ Channel Kir3.1KgaKgb1Potassium Channel - Inwardly Rectifying Subfamily J Member 3 |
| Database Links | Reactome: R-RNO-1296041Reactome: -RNO-997272 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-G Protein-Activated Inward Rectifier Potassium Channel 1 antibodyAnti-Girk-1 antibodyAnti-Inward Rectifier K(+ Channel Kir3.1 antibodyAnti-Kga antibodyAnti-Kgb1 antibodyAnti-Potassium Channel - Inwardly Rectifying Subfamily J Member 3 antibodyAnti-Kcnj3 antibodyAnti-Girk1 antibodyAnti-Kga antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
