Function | Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. |
Protein Name | Gamma-Glutamyl HydrolaseConjugaseGhGamma-Glu-X Carboxypeptidase |
Database Links | Reactome: R-HSA-6798695 |
Cellular Localisation | SecretedExtracellular SpaceLysosomeMelanosomeWhile Its Intracellular Location Is Primarily The LysosomeMost Of The Enzyme Activity Is SecretedIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
Alternative Antibody Names | Anti-Gamma-Glutamyl Hydrolase antibodyAnti-Conjugase antibodyAnti-Gh antibodyAnti-Gamma-Glu-X Carboxypeptidase antibodyAnti-GGH antibody |
Information sourced from Uniprot.org