| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GFAP |
| Gene ID: | 2670 |
| Uniprot ID: | GFAP_HUMAN |
| Immunogen Region: | 1-75 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-75 of human GFAP (NP_002046.1). |
| Immunogen Sequence: | MERRRITSAARRSYVSSGEM MVGGLAPGRRLGPGTRLSLA RMPPPLPTRVDFSLAGALNA GFKETRASERAEMME |
| Tissue Specificity | Expressed in cells lacking fibronectin. |
| Post Translational Modifications | Phosphorylated by PKN1. |
| Function | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
| Protein Name | Glial Fibrillary Acidic ProteinGfap |
| Database Links | Reactome: R-HSA-1251985Reactome: R-HSA-9613829 |
| Cellular Localisation | CytoplasmAssociated With Intermediate Filaments |
| Alternative Antibody Names | Anti-Glial Fibrillary Acidic Protein antibodyAnti-Gfap antibodyAnti-GFAP antibody |
Information sourced from Uniprot.org