| Function | Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylethanolamine (lyso-PE) and lysophosphatidylcholine (lyso-PC). May be involved in bioactive N-acylethanolamine biosynthesis from both N-acyl-lysoplasmenylethanolamin (N-acyl-lysoPlsEt) and N-acyl-lysophosphatidylethanolamin (N-acyl-lysoPE). In addition, hydrolyzes glycerophospho-N-acylethanolamine to N-acylethanolamine. Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine. |
| Protein Name | Lysophospholipase D Gdpd1Glycerophosphodiester Phosphodiesterase 4Glycerophosphodiester Phosphodiesterase Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-6814848 |
| Cellular Localisation | CytoplasmMembraneMulti-Pass Membrane ProteinPerinuclear RegionEndoplasmic ReticulumConcentrated At The Perinuclear Region And The Cell Periphery |
| Alternative Antibody Names | Anti-Lysophospholipase D Gdpd1 antibodyAnti-Glycerophosphodiester Phosphodiesterase 4 antibodyAnti-Glycerophosphodiester Phosphodiesterase Domain-Containing Protein 1 antibodyAnti-GDPD1 antibodyAnti-GDE4 antibody |
Information sourced from Uniprot.org
