| Short Description : | Rabbit polyclonal GDI1 (188-447) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GDI1 |
| Gene ID: | 2664 |
| Uniprot ID: | GDIA_HUMAN |
| Immunogen Region: | 188-447 |
| Immunogen Sequence: | ALALYRTDDYLDQPCLETVN RIKLYSESLARYGKSPYLYP LYGLGELPQGFARLSAIYGG TYMLNKPVDDIIMENGKVVG VKSEGEVARCKQLICDPSYI PDRVRKAGQVIRIICILSHP IKNTNDANSCQIIIPQNQVN RKSDIYVCMISYAHNVAAQG KYIAIASTTVETTDPEKEVE PALELLEPIDQKFVAISDLY EPIDDGCESQVFCSCSYDAT THFETTCNDIKDIYKRMAG |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 188-447 of human GDI1 (NP_001484.1). |
| Tissue Specificity | Brain.predominant in neural and sensory tissues. |
| Function | Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. |
| Protein Name | Rab Gdp Dissociation Inhibitor AlphaRab Gdi AlphaGuanosine Diphosphate Dissociation Inhibitor 1Gdi-1Oligophrenin-2Protein Xap-4 |
| Database Links | Reactome: R-HSA-8876198 |
| Cellular Localisation | CytoplasmGolgi ApparatusTrans-Golgi Network |
| Alternative Antibody Names | Anti-Rab Gdp Dissociation Inhibitor Alpha antibodyAnti-Rab Gdi Alpha antibodyAnti-Guanosine Diphosphate Dissociation Inhibitor 1 antibodyAnti-Gdi-1 antibodyAnti-Oligophrenin-2 antibodyAnti-Protein Xap-4 antibodyAnti-GDI1 antibodyAnti-GDIL antibodyAnti-OPHN2 antibodyAnti-RABGDIA antibodyAnti-XAP4 antibody |
Information sourced from Uniprot.org
