| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-GCIP/MAID (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000. WB: Preliminary experiments gave an approx 55kDa band in K562 lysate at 0.5ug/ml. This band was successfully blocked by incubation with the immunising peptide. Please note that currently w |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CCNDBP1 |
| Gene ID: | 23582 |
| Uniprot ID: | CCDB1_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_036274.3; NP_411241.1 |
| Specificity: | This antibody is expected to recognise both human isoforms of this protein. |
| Immunogen Sequence: | NRIKELTQSELEL |
| Post Translational Modifications | Phosphorylated. |
| Function | May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription. |
| Protein Name | Cyclin-D1-Binding Protein 1 Grap2 And Cyclin-D-Interacting Protein Human Homolog Of Maid |
| Cellular Localisation | Cytoplasm Nucleus |
| Alternative Antibody Names | Anti-Cyclin-D1-Binding Protein 1 antibody Anti-Grap2 And Cyclin-D-Interacting Protein antibody Anti-Human Homolog Of Maid antibody Anti-CCNDBP1 antibody Anti-DIP1 antibody Anti-GCIP antibody Anti-HHM antibody |
Information sourced from Uniprot.org