| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Cytosolic beta-glucosidase (291-340 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GBA3 |
| Gene ID: |
57733 |
| Uniprot ID: |
GBA3_HUMAN |
| Immunogen Region: |
291-340 aa |
| Specificity: |
CBG Polyclonal Antibody detects endogenous levels of CBG protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human GBA3 at the amino acid range 291-340 |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides. Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear. Hydrolyzes galactosylceramides/GalCers, glucosylsphingosines/GlcSphs and galactosylsphingosines/GalSphs. However, the in vivo relevance of these activities is unclear. It can also hydrolyze a broad variety of dietary glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens in vitro and could therefore play a role in the metabolism of xenobiotics. Possesses transxylosylase activity in vitro using xylosylated ceramides/XylCers (such as beta-D-xylosyl-(1<->1')-N-acylsphing-4-enine) as xylosyl donors and cholesterol as acceptor. Could also play a role in the catabolism of cytosolic sialyl free N-glycans. |
| Protein Name | Cytosolic Beta-GlucosidaseCytosolic Beta-Glucosidase-Like Protein 1Cytosolic GalactosylceramidaseCytosolic GlucosylceramidaseCytosolic GlycosylceramidaseCytosolic GcaseGlucosidase Beta Acid 3Glucosylceramidase Beta 3Klotho-Related ProteinKlrp |
| Database Links | Reactome: R-HSA-1660662 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Cytosolic Beta-Glucosidase antibodyAnti-Cytosolic Beta-Glucosidase-Like Protein 1 antibodyAnti-Cytosolic Galactosylceramidase antibodyAnti-Cytosolic Glucosylceramidase antibodyAnti-Cytosolic Glycosylceramidase antibodyAnti-Cytosolic Gcase antibodyAnti-Glucosidase Beta Acid 3 antibodyAnti-Glucosylceramidase Beta 3 antibodyAnti-Klotho-Related Protein antibodyAnti-Klrp antibodyAnti-GBA3 antibodyAnti-CBG antibodyAnti-CBGL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
