Anti-GATAD2B antibody (1-120) (STJ111801)

Name: Anti-GATAD2B antibody (1-120) (STJ111801)
SKU: STJ111801
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ111801

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Short Description	Rabbit polyclonal GATAD2B (1-120) antibody for use in WB, IHC-P, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IP/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:50-1:200 IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cells ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	GATAD2B
Gene ID	57459
Uniprot ID	P66B_HUMAN
Immunogen Region	1-120
Immunogen Sequence	MDRMTEDALRLNLLKRSLDP ADERDDVLAKRLKMEGHEAM ERLKMLALLKRKDLANLEVP HELPTKQDGSGVKGYEEKLN GNLRPHGDNRTAGRPGKENI NDEPVDMSARRSEPERGRLT
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human GATAD2B (NP_065750.1).

Tissue Specificity	Widely expressed.
Function	Transcriptional repressor. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development.
Protein Name	Transcriptional Repressor P66-Beta Gata Zinc Finger Domain-Containing Protein 2b P66/P68
Database Links	Reactome: R-HSA-3214815 Reactome: R-HSA-427389 Reactome: R-HSA-6804758 Reactome: R-HSA-73762 Reactome: R-HSA-8943724 Reactome: R-HSA-9679191 Reactome: R-HSA-9843940 Reactome: R-HSA-9844594 Reactome: R-HSA-9845323
Cellular Localisation	Nucleus Speckle Nucleus Chromosome Speckled Nuclear Localization Requires Both Cr1 And Cr2 Regions Localizes To Sites Of Dna Damage
Alternative Antibody Names	Anti-Transcriptional Repressor P66-Beta antibody Anti-Gata Zinc Finger Domain-Containing Protein 2b antibody Anti-P66/P68 antibody Anti-GATAD2B antibody Anti-KIAA1150 antibody

Information sourced from Uniprot.org