| Host: | Rabbit |
| Applications: | WB/IHC-P/ICC/IF/FC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-GATAD2A for use in WB, IHC-P, ICC, IF and FC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R04-7T4 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Purified |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200FC 1:50-1:100 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | GATAD2A |
| Gene ID: | 54815 |
| Uniprot ID: | P66A_HUMAN |
| Immunogen: | A synthesized peptide derived from human p66 alpha |
| Tissue Specificity | Ubiquitous, both in fetal and adult tissues. |
| Function | Transcriptional repressor. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2B. |
| Protein Name | Transcriptional Repressor P66-AlphaHp66alphaGata Zinc Finger Domain-Containing Protein 2a |
| Database Links | Reactome: R-HSA-3214815Reactome: R-HSA-427389Reactome: R-HSA-6804758Reactome: R-HSA-73762Reactome: R-HSA-8943724Reactome: R-HSA-9679191Reactome: R-HSA-9843940Reactome: R-HSA-9844594Reactome: R-HSA-9845323 |
| Cellular Localisation | Nucleus SpeckleNucleusChromosomeSpeckled Nuclear Localization Requires Both Cr1 And Cr2 RegionsLocalizes To Sites Of Dna Damage In A Manner Partially Dependent On Zmynd8 |
| Alternative Antibody Names | Anti-Transcriptional Repressor P66-Alpha antibodyAnti-Hp66alpha antibodyAnti-Gata Zinc Finger Domain-Containing Protein 2a antibodyAnti-GATAD2A antibody |
Information sourced from Uniprot.org